Job Description
Join WuXi Biologics Singapore as a Supervisor, Drug Substance Upstream Process and be part of an exciting journey in shaping a state-of-the-art greenfield biologics manufacturing facility. This is a unique opportunity to contribute to the development and operation of cutting-edge biopharmaceutical production capabilities in Singapore.
In this leadership role, you will oversee upstream processing activities for drug substance manufacturing, ensuring the highest standards of quality, safety, and efficiency. You will work closely with cross-functional teams to establish robust processes, implement best practices, and drive continuous improvement initiatives that align with global regulatory requirements.
WuXi Biologics offers a dynamic and collaborative work environment where your expertise will directly impact our mission to deliver life-changing biologics to patients worldwide. This position provides exposure to advanced technologies and the chance to build and mentor a high-performing team in a rapidly growing organization.
Responsibilities
- Supervise and lead upstream cell culture operations for drug substance manufacturing, ensuring optimal cell growth and productivity
- Develop and implement SOPs, batch records, and process controls for upstream processing activities
- Monitor and analyze process performance metrics, identifying opportunities for optimization and yield improvement
- Ensure compliance with cGMP, FDA, EMA, and HSA regulations throughout all manufacturing operations
- Coordinate with downstream, analytical, and quality teams to ensure seamless production workflows
- Mentor and develop team members, fostering a culture of safety, quality, and continuous learning
- Participate in tech transfer activities, process validation, and scale-up projects as required
- Maintain accurate documentation and support regulatory inspections and audits
Qualifications
- Bachelor's or Master's degree in Biotechnology, Chemical Engineering, Life Sciences, or related discipline
- Minimum 5 years of experience in biopharmaceutical manufacturing, with at least 2 years in a supervisory or leadership role
- Strong expertise in mammalian cell culture, bioreactor operations, and upstream process development
- Proven knowledge of cGMP regulations and ICH guidelines for biologics manufacturing
- Excellent leadership, communication, and problem-solving skills
- Experience with process scale-up, tech transfer, or validation activities is highly desirable
- Proficiency in using data analysis tools and process monitoring systems
- Ability to work in a fast-paced environment and manage multiple priorities effectively